He is voiced by Jon Lovitz, except for a brief appearance in "The Front" (1993), in which he was voiced by Dan Castellaneta.Ziff first appears in "The Way We Was" (1991), in which he takes a young Marge Bouvier to senior prom.His appearance and name are inspired by Pulitzer winning journalist Ernie Pyle.
However, this would contradict the earlier episode when it is revealed that Seymour is not her birth son.
In "Grade School Confidential", it is revealed that Agnes enjoys collecting pictures of cakes that she cuts out of magazines, a hobby she began in 1941. In the twenty sixth season episode "Sky Police" she mentions that she has a brother Stevie.
In "Half-Decent Proposal" (2002), Marge learns that Artie is extremely wealthy, having made his fortune in computers by inventing an adapter that turns dial-up modem handshaking noises into easy-listening music, and she reluctantly accepts a $1 million offer to spend a weekend at his mansion to pay for an operation Homer needs to cure his extremely loud snoring.
Homer assumes the two are having an affair, but Artie admits that he could not win her over.
She debuts in "$pringfield", where it is explained she was captured from the wild by Ernst and Gunter. Arnie Pye (voiced by Dan Castellaneta) is a disgruntled, somewhat eccentric helicopter traffic reporter for Springfield's KBBL-TV (Channel 6).
She reappears in "Viva Ned Flanders", performing in Las Vegas. He dislikes pompous anchorman Kent Brockman, with whom he often gets into arguments on the air.
The show is a huge hit that ruins Krusty's career, but Bart then ruins Gabbo's future by capturing him making a rude comment on TV.
The pair are later reduced to low-paying work such as a show at an Indian casino.
Brockman once snarled that Pye was a "jackass", with Arnie responding that he believes Kent's soul is "as black as the ace of spades".
He sometimes attempts to join the action himself, such as his attempting to hit a fleeing Homer Simpson's car with a shoe in Children of a Lesser Clod.
In "Boy Meets Curl", it is revealed that Agnes' resentment towards Seymour may have begun even before her son was born – during the 1952 Summer Olympics in Helsinki, Agnes competed in the pole vaulting event while 9-months pregnant.